情景重现
很多老师咨询能否以简单些的思路发一篇中医药复方相关的1区2区文章,用于博士毕业或晋升。那我就建议大家可以用这套思路:
1.中药成分鉴定或含药血清入血成分鉴定;
2.根据入血成分鉴定结果去做网络药理学分析,预测靶点和途径;
3.做相关疾病动物实验,并开展组学研究(也有文献把药效放第1部分);
4.网药结合组学,确定该中药对疾病的把靶点途径;
5.对预测确定的靶点途径进行验证(比如铁死亡、线粒体功能紊乱),可以用动物或细胞实验。
案例分析
1.Phytomedicine( IF8.3中科院1区top):Immunomodulatory mechanism of Huangqi-Guizhi-Wuwu Decoction in alleviating autoimmune arthritis based on network pharmacology and experimental validation
![]()
2.Chinese Medicine( IF 5.7 中科院2区):Metabolomics integrated with network pharmacology of blood-entry constituents reveals the bioactive component of Xuefu Zhuyu decoction and its angiogenic effects in treating traumatic brain injury
![]()
图文摘要:
![]()
3.
Journal of Ethnopharmacology (IF 5.4,中科院2区)
The active components and potential mechanisms of Wuji Wan in the treatment of ethanol-induced gastric ulcer: An integrated metabolomics, network pharmacology and experimental validation
图文摘要:
![]()
4.Phytomedicine( IF8.3中科院1区top):Xiao-Feng Xuan-Qiao decoction alleviates allergic rhinitis by inhibiting neutrophil extracellular trap formation
图文摘要:
![]()
5.
Journal of Ethnopharmacology (IF 5.4,中科院2区)
:Buyang Huanwu Decoction attenuatesvascular aging by suppressing the pathwayof neutrophil extracellular trap formationvia modulation of the HMGB1/TLR4/p38signaling pathway
![]()
中医药基础科研技术服务及加群交流:
相关咨询,加微信:RumferSCI-1。
【福利时刻】科研服务(点击查看):、、、、、。咨询加微信:1278317307。
特别声明:以上内容(如有图片或视频亦包括在内)为自媒体平台“网易号”用户上传并发布,本平台仅提供信息存储服务。
Notice: The content above (including the pictures and videos if any) is uploaded and posted by a user of NetEase Hao, which is a social media platform and only provides information storage services.